The shooting occurred in an area near a planned police support rally and counterprotest, Denver Police Public Information Officer Ana Munoz told CNN over the phone Saturday night.
Munoz did not have information on whether the shooting was related to the protests or if the victim or suspect were a part of the protests.
Officers on the scene rendered aid to the victim, who was transported to a hospital where they were later pronounced dead, Investigations Division Chief Joe Montoya said during a press conference Saturday.
No further information about the incident, or if the parties involved in the shooting were affiliated with groups at the protest were given.
Police are interviewing witnessing and reviewing video of shooting, Montoya said.
Initially, Denver police tweeted two people were taken into custody as a result of the shooting, but only one person was taken into custody, Montoya said.